2010 Mercedes-Benz E350 recalls and problems

The 2010 Mercedes-Benz E350 has 4 safety recalls and 184 owner complaints filed with NHTSA. Recall repairs are free at any Mercedes-Benz dealer.

Recalls
4
Complaints
184
Crashes / fires
9 / 0
Injuries / deaths
6 / 0

Recalls may cover only some 2010 Mercedes-Benz E350 vehicles. Check your VIN at NHTSA ↗ to see open recalls for your exact car.

2010 Mercedes-Benz E350 recalls

Recall 22V-168: Engine and Engine Cooling, Electronic Stability Control (ESC), Exterior Lighting

Reported Mar 18, 2022 · 22 vehicles affected · Mercedes-Benz USA, LLC

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2010 E350, 2014 G550, 2008-2009 C300, 2008 C350, 2009 CLK550, 2007 SL550, SLK280, and 2008 SLK350 vehicles. Various control units may have been updated with incorrect software configuration during a service repair. This can result in various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions, including stability and traction control.

Risk: Various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions including stability and traction control, can increase the risk of a crash.

Fix: Dealers will update the software configuration on the affected control units, free of charge. Owner notification letters were mailed May 3, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040003.

Recall 18V-043: Air Bags

Reported Jan 10, 2018 · 132,167 vehicles affected · Mercedes-Benz USA, LLC.

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2013 C250, C250 Coupe, C350 Coupe 4Matic, C300 4Matic, C350, C350 Coupe, C63 AMG, C63 Coupe, E350 Cabrio, E350 Coupe, E550 Cabrio, E350 Coupe 4Matic, E550 Coupe, GLK350 4Matic, GLK250 Bluetec 4Matic, GLK350, SLS Coupe, SLS AMG GT Coupe, and SLS Roadster vehicles sold, or ever registered, in the states of Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands or "Zone A." Additionally, MBUSA is recalling certain 2010 C300, C300 4Matic, C63 AMG, E350 Coupe, E550 Coupe, GLK350, and GLK350 4Matic vehicles ever registered in the states of Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia or "Zone B." MBUSA is also recalling certain 2009 C300, C300 4Matic, C63 AMG, and C350 vehicles ever registered in the states of AK, CO, CT, ID, IA, ME, MA, MI, MN, MO, NH, NY, ND, OR, RI, SD, UT, VT, WA, WI and WY or "Zone C." In the event of a crash necessitating deployment of the passenger frontal air bag, these passenger air bag inflator may explode due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.

Risk: An inflator explosion may result in sharp metal fragments striking the driver or other occupants resulting in serious injury or death.

Fix: MBUSA will notify owners, and dealers will replace the passenger frontal air bag module, free of charge. Mercedes issued an interim notification to owners on February 23, 2018. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.

Recall 16V-363: Air Bags

Reported May 26, 2016 · 258,163 vehicles affected · Mercedes-Benz USA, LLC.

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain model year 2008-2011 C300 Sedan, C300 4matic Sedan, C350 Sedan, C63 AMG Sedan vehicles, 2010-2011 GLK350, GLK350 4-Matic and E350 Coupe vehicles, 2011 SLS AMG, E350 Convertible, E550 Coupe and E550 Convertible vehicles originally sold, or ever registered, in Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands, or "Zone A." Additionally, unless included in "Zone A" above, MBUSA is recalling certain model year 2008 C300 Sedan, C350 Sedan, C63 AMG Sedan and C300 4-Matic Sedan vehicles originally sold, or ever registered, in Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia, or "Zone B." Vehicles not originally sold or ever registered in either Zones A or B are not subject to this safety recall. These vehicles are equipped with certain air bag inflators assembled as part of the passenger frontal air bag modules, and used as original equipment or replacement equipment. In the event of a crash necessitating deployment of the front air bags, these inflators may rupture due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.

Risk: An inflator rupture may result in metal fragments striking the vehicle occupants resulting in serious injury or death.

Fix: MBUSA will notify owners, and dealers will replace the passenger frontal air bag modules, free of charge. Owners were sent an interim notification October 2016. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.

Recall 16V-081: Air Bags

Reported Feb 11, 2016 · 711,159 vehicles affected · Mercedes-Benz USA, LLC.

Problem: Mercedes-Benz USA, LLC. (MBUSA) is recalling certain model year 2009-2010 ML320 BlueTec 4Matic, GL320 BlueTec 4Matic and R320 CDI 4Matic, 2011 E350 Cabriolet and E550 Cabriolet, 2009-2011 ML350, ML350 4Matic, ML550 4Matic, ML63 AMG, and C63 AMG, 2010-2011 ML450 4Matic Hybrid, E350 Coupe, E350 4Matic, E550 Coupe, E550 4Matic, and E63 AMG, 2011-2012 GL350 BlueTec 4Matic and R350 BlueTec 4Matic, 2009-2012 GL450 4Matic, GL550 4Matic and R350 4Matic, 2007-2008 SLK280, SLK350, and SLK55 AMG, 2011-2014 SLS AMG Coupe, 2012 SLS AMG Cabriolet, 2013-2014 SLS AMG GT and SLS AMG GT Cabriolet, 2005 C230 Kompressor and C320, 2006-2007 C230, 2006-2011 C350, 2008-2011 C300 and C300 4Matic, 2010-2012 GLK350 and GLK350 4Matic and 2007-2008 Chrysler Crossfire vehicles. Upon deployment of the driver's frontal air bag, excessive internal pressure may cause the inflator to rupture.

Risk: In the event of a crash necessitating deployment of the driver's frontal air bag, the inflator could rupture with metal fragments striking the driver or other occupants resulting in serious injury or death.

Fix: MBUSA will their notify owners, and Fiat Chrysler will notify the affected Chrysler owners. Dealers for the respective brands will replace the driver's frontal air bag module, free of charge. This recall began November 2016. Mercedes-Benz owners may contact MBUSA customer service at 1-800-367-6372 and Chrysler owners may contact Fiat Chrysler customer service at 1-800-853-1403.

2010 Mercedes-Benz E350 problems reported by owners

Problem areaReports
Air Bags68
Unknown or Other19
Fuel/Propulsion System18
Electrical System17
Suspension17
Engine15
Power Train14
Structure11
Service Brakes11
Steering8
Exterior Lighting5
Vehicle Speed Control4

Most reported parts

  • Structure › Body — 9
  • Lane Departure › Blind Spot Detection — 2
  • Engine and Engine Cooling › Exhaust System — 1
  • Power Train › Automatic Transmission — 1
  • Equipment › Electrical › Radio/Tape Deck/Cd Etc. — 1
  • Electrical System › Horn — 1
  • Tires › Tread/Belt — 1
  • Service Brakes, Hydraulic › Power Assist › Vacuum › Hoses, Lines/Piping, and Fittings — 1

Typical mileage at the time of the problem: 60,000 miles (median of owner reports).

Problems that are not covered by a recall are paid repairs; labor rates follow local mechanic pay — see what auto mechanics earn in each state.

Recent 2010 Mercedes-Benz E350 complaints

Owner reports filed with NHTSA, as written (personal details removed). Complaints are not verified by NHTSA.

Steering · reported Sep 30, 2026
While I was driving the Issues with the steering column module (SCM) sudden loss of critical driver controls, erratic electrical behavior. It failed to communicate properly with the power steering system, alongside dashboard warnings for the Electronic Stability Program (ESP) and Antilock Braking System (ABS) now my car is parked and I can’t drive it. I had to call a tow truck to take it home.
Service Brakes · reported Apr 10, 2026
I am writing to formally submit a complaint regarding my 2010 E350 (VIN # [XXX] ). I have taken great pride in owning and maintaining this vehicle, and I want to share my concerns based on my recent experience. I have consistently kept this car well-maintained, following all recommended service schedules and ensuring that any necessary repairs were handled promptly. Up until now, I have not experienced any significant issues with the vehicle. It has been reliable, well cared for, and in excellent condition. Recently, when the brake line indicator came on, I immediately took the vehicle to a…
Exterior Lighting · reported Feb 17, 2026
All of sudden blind spot inoperable , turning signal to Rt. , signal goes LT. OR TURNING SIGNAL TO LT. , SIGNAL GOES To RT.
Service Brakes · reported Jan 19, 2026
Car was found to have the rear subframe corrosion for issue. But also the brake lines were corroded very badly. They should be covered under the rear subframe extended warranty replacement. The rear brake lines are an frequent issue and almost always shows up when the subframe begins to rot. Also the pattern of the corrosion seems to be consistent across multiple incidents. Look at photos I uploaded and the Reddit post; identical. Look at this post from Reddit, almost identical corrosion on the rear brake lines as mine. Furthermore, it always is the rear brake lines, almost never the front.…
Service Brakes · reported Nov 24, 2025
It seems like brake lines corroded and need to be replaced. Same issue in this car with subframe and that was taken care of by the extended warranty but brake lines were not part of extended warranty? That should be investigated further. Rear subframe rust out and brake line corrosion are obviously related but Mercedes is only addressing subframe. Why? A lot of people have this issue and it's a huge safety concern.

Other Mercedes-Benz E350 years

Compare all Mercedes-Benz E350 years · All Mercedes-Benz models

Frequently asked questions

Does the 2010 Mercedes-Benz E350 have any recalls?

Yes — NHTSA lists 4 recalls for the 2010 Mercedes-Benz E350: 22V-168 (engine and engine cooling, electronic stability control (esc), exterior lighting), 18V-043 (air bags), 16V-363 (air bags), 16V-081 (air bags). Not every vehicle is affected, so check your VIN at nhtsa.gov/recalls.

What is the most common problem with the 2010 Mercedes-Benz E350?

Owners report air bags problems most often (68 reports), followed by unknown or other (19). The typical mileage when problems were reported is about 60,000 miles.

Are Mercedes-Benz recall repairs free?

Yes. Safety recall repairs are free at authorized Mercedes-Benz dealers, whether you are the first owner or bought the car used.